IMAGINE project
Excessive and inappropriate use of antibiotics is the main driver of antimicrobial resistance, posing a significant risk, especially for frail older adults in nursing homes who are vulnerable to frequent and severe infections. To address this, the IMAGINE project has supported healthcare professionals across 8 European countries to improve infection prevention and promote appropriate antibiotic use. By implementing a multifaceted intervention, data has been collected before and after to evaluate its impact across all participating facilities.
Key results
%
Reduction in urinary
tract infections after
intervention
Nursing, medical, and care professionals involved
MORE THAN
PEOPLE
%
Reduction in
inappropriate
prescriptions of antibiotic
Annual net savings across Europe
MILLIONS OF EUROS €
%
Increase of available resources
and hygiene measures for staff
Project tools
The aim was to increase the prevention of infections and reduce inappropriate antibiotic use by implementing a multifaceted intervention targeting health care professionals (HCPs) in nursing homes across eight European countries: Greece, Hungary, Lithuania, Poland, Slovakia, Slovenia, Spain, and Denmark.
The project has been structured around a three-phase intervention methodology. It has included two clinical audits, with an in-person multifaceted intervention for healthcare professionals conducted between them.
The audits have been carried out to evaluate both antibiotic prescribing practices, using the APO method, and infection prevention and control (IPC) measures, assessed through the IPC audit tool.
Between these two audits, nursing home healthcare staff have participated in a structured, face-to-face multifaceted intervention aimed at improving clinical practices.
IMAGINE Final Conference
Barcelona, December 12th 2025
The European project IMAGINE will hold its Final Conference on 12 December 2025 in Barcelona. The event will bring together representatives from European institutions, consortium partners, and key stakeholders to present the main results, achievements, and future perspectives of the project.
You may consult the final programme and register by contacting the organisers at [email protected]










